Data on the effectiveness of on-demand PrEP is only available for gay men, MSM and transgender women. The
clinical study which tested this effectiveness showed that on-demand PrEP reduced the risk of acquiring HIV by 86%,
which was the same level of protection provided by a study of daily PrEP use. Importantly, there were no cases of
people acquiring HIV during the trial among participants who used the medication as prescribed.

Click here to access an AFAO fact Sheet regarding PrEP on Demand