Studies involving men who have sex with men include; IPrEx, Proud Study and IPERGAY. To date, studies have shown PrEP to be safe and highly effective in preventing HIV infections.
Various PrEP study results may seem confusing and at times conflicting but the simple message is, adhering to PrEP as directed by your doctor can offer you very high levels of protection from acquiring HIV. HIV experts suggest that if used correctly, PrEP can offer up to 99% protection from HIV. The key to effective HIV protection from using PrEP is adherence.
PROUD Study
Article Proud Study
‘…findings strongly support the addition of PrEP to the standard of prevention for men who have sex with men at risk of HIV infection’
PROUD PrEP study results published
Pre-exposure prophylaxis (PrEP) stops 86% of HIV infections in PROUD study
Presentation PROUD Study
Pragmatic Open-Label Randomised Trial of Pre exposure Prophylaxis: The PROUD Study
By Sheena McCormack
MRC Clinical Trails Unit at University College London, London, United Kingdom.
Conference of Retroviral and Opportunistic Infections (CROI), 2015.
IPERGAY Study
Article IPERGAY STUDY
‘…certainly no evidence that anyone who had been taking Truvada had become infected’
Molina J-M et al. On Demand PrEP With Oral TDF-FTC in MSM: Results of the ANRS Ipergay Trial. 2015 Conference on Retroviruses and Opportunistic Infections (CROI), Seattle, USA, abstract 23LB, 2015.
Pre-exposure prophylaxis also stops 86% of HIV infections in Ipergay study
Presentation IPERGAY
On Demand PrEP With Oral TDF-FTC in MSM: Results of the ANRS Ipergay Trial
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Jean-Michel Molina
University of Paris Diderot, Paris, France.
Conference of Retroviral and Opportunistic Infections (CROI), 2015.
San Francisco Program
Article San Francisco Program
No HIV infections seen in San Francisco PrEP users referred via primary care
‘…not seen a single HIV infection in people using PrEP since it started in 2012’
No HIV infections seen in San Francisco PrEP users referred via primary care
Presentation San Francisco Program
Scale-Up of Pre exposure Prophylaxis in San Francisco to Impact HIV Incidence
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Robert M. (2015) Grant Scale-Up of Pre exposure Prophylaxis in San Francisco to Impact HIV Incidence
Gladstone Institutes, San Francisco, CA, United States
Robert M. Grant
Gladstone Institute, San Francisco, CA, United States.
Conference of Retroviral and Opportunistic Infections (CROI), 2015.
IpREx Study
Article IpREx Study
‘Overall PrEP effectiveness in iPrEx OLE study 50%, but 100% in those taking four or more doses a week’
‘…there were no infections in participants with drug levels consistent with taking PrEP at least four times a week’
Results of the iPrEx open-label extension
How will people use PrEP? iPrEx users talk condoms, pills, anxiety and relief